has been shown to inhibit acid secretion to a similar extent as Omeprazole, without any significant differences between the two compounds in vitro. is the s-isomer of Omeprazole, which is a racemate of the S- and R-enantiomer. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.Įsomeprazol Sandoz I.v. By doing so, it inhibits acid secretion into the gsatric lumen. belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H +/K + ATPase at the secretory surface of the gastric parietal cell. pylori eradication to reduce the risk of duodenal ulcer recurrence. is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H.
It is the S-isomer of omeprazole.Įsomeprazol Sandoz I.v. is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell.